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Sun, 21 Mar 2010 18:51:00 GMT

Sex on the brain: 'Doublesex' gene key to determining fruit fly gender

The brains of males and females, and how they use them, may be far more different then previously thought, at least in the fruit fly Drosophila melanogaster, according to research funded by the Wellcome Trust. In a paper published today in the journal
Sun, 21 Mar 2010 18:51:00 GMT

Caltech-led team provides proof in humans of RNA interference using targeted nanoparticles

Researchers unveil scientific results from siRNA Phase I clinical trial in cancer patients IMAGE:This targeted nanoparticle used in the study and shown in this schematic is made of a unique polymer and can make its way to human tumor cells in a
Sun, 21 Mar 2010 18:51:00 GMT

Newly identified growth factor promotes stem cell growth, regeneration

DURHAM, N.C. -- Scientists at Duke University Medical Center have identified a new growth factor that stimulates the expansion and regeneration of hematopoietic (blood-forming) stem cells in culture and in laboratory animals. The discovery, appearing in
Sun, 21 Mar 2010 18:50:00 GMT

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Extract not available.
Sun, 21 Mar 2010 18:45:00 GMT

Gene-Targeted Cancer Fix Could Be a Breakthrough

For first time in humans, scientists used RNA to stop production of protein driving malignancy
Sun, 21 Mar 2010 18:23:00 GMT

Gene-Targeted Cancer Fix Could Be a Breakthrough (HealthDay)

SUNDAY, March 21 (HealthDay News) -- For the first time in humans, scientists have successfully used a gene-manipulation therapy to enter tumor cells and block the production of toxic proteins that are causing cancer, researchers report. "They're
Sun, 21 Mar 2010 18:22:00 GMT

Red coral left 'unprotected' at wildlife trade talks

DOHA (AFP) The UN wildlife trade body on Sunday rejected by secret ballot a proposal to require trade and scientific monitoring for precious red and pink corals harvested in the Mediterranean and the western Pacific. The Conference on International
Sun, 21 Mar 2010 16:03:00 GMT

Son's DNA can be used at father's trial, judge rules

RENO, Nev. — DNA taken from the young son of a man accused of killing a college student and raping two other women can be used as evidence in his upcoming trial to try to link the suspect to the crimes, a judge ruled. Âlong_space Washoe District
Sun, 21 Mar 2010 13:40:00 GMT

DNA: Son's DNA can be used at father's trial

RENO, Nev. — DNA taken from the young son of a man accused of killing a college student and raping two other women can be used as evidence in his upcoming trial to try to link the suspect to the crimes, a judge ruled. Âlong_space Washoe District
Sun, 21 Mar 2010 13:39:00 GMT

Map Your Genomes For $48,000

If you're concerned about a particular medical condition or merely have a sincere interest in your genetic make-up then for $48,00, Illumina will map your genomes. Read the rest of the story at:
Sun, 21 Mar 2010 12:36:00 GMT

Novel method helps researchers perform targeted sequencing in maize genome

MADISON, Wis. -- Researchers from Iowa State University, University of Minnesota, University of Florida and Roche NimbleGen have published a novel method to perform targeted sequencing in the highly complex maize genome. The method, which can be easily
Sun, 21 Mar 2010 09:51:00 GMT

Behaviour of single protein observed in unprecedented detail by Stanford chemists

For the first time, researchers have been able to confine and study an individual protein, one that plays a key role in photosynthesis, without having to pin it down so tightly as to alter its fundamental behaviour. In the first practical application to
Sun, 21 Mar 2010 01:22:00 GMT

Light activated 'warhead' turns modest molecules into super protein killers

Using a novel light activation technique, scientists have been able to turn molecules with only a modest ability to fight specific proteins into virtual protein destroyers. The new technique, which uses a 'warhead' molecule capable of inactivating nearby
Sun, 21 Mar 2010 01:22:00 GMT

Antifreeze proteins can stop ice melting, Queen's professors find

The same antifreeze proteins that keep organisms from freezing in cold environments can also prevent ice from melting at warmer temperatures, according to a new Queen's University study. The study presents the first direct measurements of the
Sun, 21 Mar 2010 01:21:00 GMT

Ben-Gurion University researcher receives rappaport prize for excellence in biomedical research

Prof. Smadar Cohen, head of the University's Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, has been awarded the prestigious Rappaport Prize for Excellence in Biomedical Research, an award totaling $100,000. The prize, given by
Sun, 21 Mar 2010 00:58:00 GMT

Antinociceptive and anti-inflammatory properties of 7-hydroxycoumarin in experimental animal models: potential therapeutic for the control of inflammatory chronic pain

Objectives In the present study we investigated the antinociceptive, anti-inflammatory and antipyretic effects of 7-hydroxycoumarin (7-HC) in animal models. Methods The effects of oral 7-HC were tested against acetic acid-induced writhing, formalin test,
Sun, 21 Mar 2010 00:06:00 GMT

The involvement of endoplasmic reticulum stress in flavonoid-induced protection on cardiac cell death caused by ischaemia/reperfusion

Objectives We have investigated whether endoplasmic reticulum stress and Bcl-2 proteins were linked to the protective effect exerted by flavonoids on ischaemia/reperfusion-induced cardiac damage. Methods Cell viability and immunoblotting were performed.
Sun, 21 Mar 2010 00:06:00 GMT

Repeated administration of oxycodone modifies the gene expression of several drug metabolising enzymes in the hepatic tissue of male Sprague-Dawley rats, including glutathione S-transferase A-5 (rGSTA5) and CYP3A2

Objectives Clinical use and illicit abuse of the potent opioid agonist oxycodone has dramatically increased over the past decade. Yet oxycodone remains one of the least studied opioids, particularly its interactions on the genomic level. The aim of this
Sun, 21 Mar 2010 00:06:00 GMT

Postdoctoral Studies in RNA Polymerase Structure and Mechanism

Extract not available.
Sat, 20 Mar 2010 23:20:00 GMT

New dinosaur species found in China

Paleontoligists in China Saturday claimed to have found the skeleton of a new species of carnivorous dinosaur that believed to have lived about 80 million years ago. Experts have found an intact and complete skeleton fossil of a previously undiscovered
Sat, 20 Mar 2010 23:13:00 GMT

A Camelid Anti-PrP Antibody Abrogates PrPSc Replication in Prion-Permissive Neuroblastoma Cell Lines

The development of antibodies effective in crossing the blood brain barrier (BBB), capable of accessing the cytosol of affected cells and with higher affinity for PrPSc would be of paramount importance in arresting disease progression in its late stage
Sat, 20 Mar 2010 20:49:00 GMT

Nerve Terminal Degeneration Is Independent of Muscle Fiber Genotype in SOD1G93A Mice

Motor neuron degeneration in SOD1G93A transgenic mice begins at the nerve terminal. Here we examine whether this degeneration depends on expression of mutant SOD1 in muscle fibers. Methodology/Principal Findings Hindlimb muscles were transplanted between
Sat, 20 Mar 2010 20:49:00 GMT

2. Research and Markets: Life Sciences Industry IT Spending Forecast in South...

Publication: Business Wire DUBLIN -- Research and Markets (http://www.researchandmarkets.com/research/b88766/life_sciences_indu) has announced the addition of the 'Life Sciences Industry IT Spending Forecast in South Korea through 2014' report to their
Sat, 20 Mar 2010 20:42:00 GMT

New dinosaur species found in China

Experts have found an intact and complete skeleton fossil of a previously undiscovered dinosaur species in north China, the team's leading scientist Xu Xing said. The species 'Linheraptor exquisitus' is the latest among the Dromaeosauridae family of the
Sat, 20 Mar 2010 20:11:00 GMT

Hot, dry and different: Australian lizard richness is unlike that of mammals, amphibians and birds

Aims (1) To map the species richness of Australian lizards and describe patterns of range size and species turnover that underlie them. (2) To assess the congruence in the species richness of lizards and other vertebrate groups. (3) To search for
Sat, 20 Mar 2010 19:17:00 GMT

Phylogenetic, spatial and environmental components of extinction risk in carnivores

Aim Extinction risk is non-randomly distributed across phylogeny and space and is influenced by environmental conditions. We quantified the relative contribution of these factors to extinction risk to unveil the underlying macroecological processes and
Sat, 20 Mar 2010 19:17:00 GMT

Sharks on the menu at wildlife trade meet (AFP)

DOHA (AFP) Four rapidly dwindling shark species prized in Asia for fins and in Europe for meat will be swimming against the current at a UN wildlife trade meet days after an attempt to protect tuna was crushed. Starting Sunday, the 175-nation Convention
Sat, 20 Mar 2010 18:00:00 GMT

Scientific breakthrough in genetic studies of animal domestication

The domestication of animals and plants is the most important technological innovation during human history. This genetic transformation of wild species has occurred as humans have used individuals carrying favourable gene variants for breeding purposes.
Sat, 20 Mar 2010 17:45:00 GMT

Genetically engineered tobacco plant cleans up environmental toxin

Tobacco might become as well known for keeping us healthy as it is for causing illness thanks to researchers from the U.K. In a new research report appearing in the March 2010 print issue of the FASEB Journal (http://www.fasebj.org) scientists explain
Sat, 20 Mar 2010 17:45:00 GMT

With just 1 enzyme missing, mice show 'global' metabolic improvements

When researchers created mice lacking an enzyme that breaks down and releases stored triglycerides (more properly known as triacylglycerols or TGs), they expected to see animals with better lipid profiles. But according to a report in the March Cell
Sat, 20 Mar 2010 17:45:00 GMT

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